Before Wu-Tang An American Saga hit the small screen, its creators Rza and Gza were in a movie together. The film's called Coffee and Cigarettes and they co-star with none other than “Ghostbusting-ass” Bill Murray in 2003. The experimental film is a series of shorts about you guessed it, coffee and cigarettes.
The movie was filmed in black and white and also featured Spike Lee, Steve Buscemi, Iggy Pop, and others. The two rappers play themselves, as does Murry so we don't know if this counts as acting but it is good for a serious laugh.