During a 2011 interview with Vibe, 2 Chainz revealed how he got the name Tity Boy saying; “The name Tity Boi actually came from my big mama, from me being spoiled and an only child—breastfed. My mama called me Tity Boi, my dad called me Tity Man, my hood called me Tit so when we was trying to rap I had been going by Tit my whole life, Tit, Tity, Tity Man —it's just like a country nickname —term for being an only child.”
2 Chainz still goes by Tity Boy, he never changed it but 2 Chainz stuck “2 Chainz made it lady and kid friendly. In my 8th grade yearbook picture I had on 2 chains. I had always been into like jewelry so 2 Chainz just stuck” – 2 Chainz told Vibe.